ace i/d and mmp-7 a-181g variants and the risk of end stage renal disease
نویسندگان
چکیده
the variants of angiotensin converting enzyme (ace) and matrix metalloproteinases (mmps) genes might be involved in the pathogenesis of end stage renal disease (esrd) and hypertension. we studied the ace insertion/deletion (i/d) and mmp-7 a-181g variants in 99 unrelated esrd patients and 117 individuals without renal complications from western iran with kurdish ethnic background. the frequency of ace i/d variants was not significantly different between esrd patients and controls. however, the presence of ace d allele increased the risk of hypertension in esrd patients by 2.14-fold (p=0.036). the mmp-7 -181 ag genotype increased the risk of esrd by 2.04 times (p=0.026). the present study indicated the absence of an association between the ace i/d polymorphism with the risk of esrd. however, the ace d allele increased the risk of hypertension in esrd patients. also, the present study suggests a role for mmp-7 ag genotype in the pathogenesis of esrd.
منابع مشابه
ACE I/D and MMP-7 A-181G variants and the risk of end stage renal disease
The variants of angiotensin converting enzyme (ACE) and matrix metalloproteinases (MMPs) genes might be involved in the pathogenesis of end stage renal disease (ESRD) and hypertension. We studied the ACE insertion/deletion (I/D) and MMP-7 A-181G variants in 99 unrelated ESRD patients and 117 individuals without renal complications from Western Iran with Kurdish ethnic background. The frequency ...
متن کاملACE I/D and MMP-7 A-181G variants and the risk of end stage renal disease
The variants of angiotensin converting enzyme (ACE) and matrix metalloproteinases (MMPs) genes might be involved in the pathogenesis of end stage renal disease (ESRD) and hypertension. We studied the ACE insertion/deletion (I/D) and MMP-7 A-181G variants in 99 unrelated ESRD patients and 117 individuals without renal complications from Western Iran with Kurdish ethnic background. The frequency ...
متن کاملthe study of practical and theoretical foundation of credit risk and its coverage
پس از بررسی هر کدام از فاکتورهای نوع صنعت, نوع ضمانت نامه, نرخ بهره , نرخ تورم, ریسک اعتباری کشورها, کارمزد, ریکاوری, gdp, پوشش و وثیقه بر ریسک اعتباری صندوق ضمانت صادرات ایران مشخص گردید که همه فاکتورها به استثنای ریسک اعتباری کشورها و کارمزد بقیه فاکتورها رابطه معناداری با ریسک اعتباری دارند در ضمن نرخ بهره , نرخ تورم, ریکاوری, و نوع صنعت و ریسک کشورها اثر عکس روی ریسک اعتباری داردو پوشش, وثی...
15 صفحه اولthe investigation of the relationship between type a and type b personalities and quality of translation
چکیده ندارد.
legal aspects of end of life and end stage disease
Abstract: Aims: End of Life (EOL) care providers potentially face by variety of legal and professional dilemma. This study is designed to review and analyze these challenges and approaches to solve them. Materials & Methods: In this narrative review study, legal aspects of end-of-life care in subjects such as medical assisted dying, decision-making capacity and withdrawal of life-sustaining...
متن کاملThe relationship between Aldosterone level and various LV conditions in patients with End-stage renal disease
Background: Aldosterone has been assumed to be implicated in left ventricular hypertrophy (LVH). Preventing the progression of LVH in the early period of end-stage renal disease (ESRD) can increase patient survival. In this study, therefore, we analyzed the relationship between aldosterone level and LVH in ESRD patients who underwent hemodialysis at Fatemeh Zahra Hospital and Imam Khomeini Hosp...
متن کاملمنابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
molecular biology research communicationsجلد ۶، شماره ۱، صفحات ۴۱-۴۴
میزبانی شده توسط پلتفرم ابری doprax.com
copyright © 2015-2023